|
KMID : 0988920190170030413
|
|
Intestinal Research
2019 Volume.17 No. 3 p.413 ~ p.418
|
|
|
Clinical comparison of low-volume agents (oral sulfate solution and sodium picosulfate with magnesium citrate) for bowel preparation: the EASE study
|
|
Kim Jee-Yeon
Kim Hyun-Gun
Kim Kyeong-Ok
Kim Hyung-Wook
Park Jong-Ha
Byeon Jeong-Sik
Hwang Sung-Wook
Shin Hyun-Deok
Shin Jeong-Eun
Yang Hyo-Joon
Lee Hyun-Seok
Jung Yun-Ho
Cho Young-Seok
Joo Young-Eun
Myung Dae-Seong
Huh Kyu-Chan
Ahn Eu-Mi
|
|
|
Abstract
|
|
|
Background/Aims: This study compared the efficacy, compliance, and safety of bowel preparation between sodium picosulfate with magnesium citrate (SPMC) and oral sulfate solution (OSS).
Methods: A prospective randomized multicenter study was performed. Split preparation methods were performed in both groups; the SPMC group, 2 sachets on the day before, and 1 sachet on the day of the procedure, the OSS group, half of the OSS with 1 L of water on both the day before and the day of the procedure. The adenoma detection rate (ADR), adequacy of bowel preparation using the Boston Bowel Preparation Scale (BBPS) score, patient satisfaction on a visual analog scale (VAS), and safety were compared between the 2 groups.
Results: This study analyzed 229 patients (121 in the SPMC group and 108 in the OSS group). ADR showed no differences between 2 groups (51.7% vs. 41.7%, P>0.05). The mean total BBPS score (7.95 vs. 8.11, P>0.05) and adequate bowel preparation rate (94.9% vs. 96.3%, P>0.05) were similar between the 2 groups. The mean VAS score for taste (7.62 vs. 6.87, P=0.006) was significantly higher in the SPMC group than in the OSS group. There were no significant differences in any other safety variables between the 2 groups except nausea symptom (36.1% vs. 20.3%, P=0.008).
Conclusions: Bowel preparation for colonoscopy using low volume OSS and SPMC yielded similar ADRs and levels of efficacy. SPMC had higher levels of satisfaction for taste and feeling than did OSS.
|
|
|
KEYWORD
|
|
|
Colonoscopy, Bowel preparation, Oral sulfate solution, Sodium picosulfate with magnesium citrate
|
|
|
FullTexts / Linksout information
|
|
 
|
|
|
Listed journal information
|
|
  
|
|